This time I decided to look into the neurodegenerative disorder, Huntington's disease. Like I just stated, Huntington's Disease impairs the growth and development of the brain and central nervous system. One of the reasons I decided to study Huntington's disease is because of how little we currently know about it. Factors such as why the disease's onset does not occur until mid-adult life, treatment, or why the disease's mutation becomes more severe as it gets passed through generations are all poorly understood. While the disease is extremely severe, it contains some fascinating molecular biology concepts that really pushed me to study this disease. Selective degeneration, experimental treatments, and neuropathological features of Huntington's disease all contribute to make it a highly interesting molecular disease to study. Again, I have created a screencast covering what I have learned about Huntington's disease, what it's causes are, and what makes this disease so lethal.
Works Cited:
"Huntington disease - Genetics Home Reference." Genetics Home Reference - Your guide to understanding genetic conditions. N.p., n.d. Web. 24 Apr. 2013. <http://ghr.nlm.nih.gov/condition/huntington-disease>
"HTT - huntingtin - Genetics Home Reference." Genetics Home Reference - Your guide to understanding genetic conditions. N.p., n.d. Web. 24 Apr. 2013. <http://ghr.nlm.nih.gov/gene/HTT>
"Huntington Disease | Learn Science at Scitable."Nature Publishing Group : science journals, jobs, and information. N.p., n.d. Web. 24 Apr. 2013. <http://www.nature.com/scitable/topicpage/huntington-s-disease-the-discovery-of-the-851>
Heils, Armin, Andreas Teufel, Susanne Petri, Gerald Stöber, Peter Riederer, Dietmar Bengel, and K. Peter Lesch. "Allelic Variation Of Human Serotonin Transporter Gene Expression." Journal of Neurochemistry 66.6 (1996): 2621-2624. Print.
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